Overview

pPLUS® AAV-RC range is a set of RepCap plasmids designed for AAV production of various serotypes.

The plasmids have been optimized for use with pPLUS® AAV-Helper in a triple transfection process, providing enhanced AAV yields of high quality and infectivity. The pPLUS® AAV-RC plasmids are readily available at Research Grade and available upon request at GMP grade.

 

 

Ordering Information

Part N° Product Quality Grade Packsize
101000214 pPLUS® AAV-RC2 R&D 1mg
101000215 pPLUS® AAV-RC2 R&D 10mg
101000216 pPLUS® AAV-RC2 R&D 100mg
101000242 pPLUS® AAV-RC5 R&D 1mg
101000243pPLUS® AAV-RC5 R&D10mg
101000244pPLUS® AAV-RC5 R&D100mg
101000245pPLUS® AAV-RC6R&D1mg
101000246pPLUS® AAV-RC6R&D10mg
101000247pPLUS® AAV-RC6R&D100mg

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Capabilities

Enhanced VG titers when used with pPLUS® AAV-Helper

pPLUS® AAV-RC are RepCap plasmids engineered for AAV production and providing a strong performance when used in combination with pPLUS® AAV-Helper and FectoVIR®-AAV. The use of pPLUS® AAV2 packaging system leads to a 1.6-to-2.4-fold increase in VG vs competitors. The use of pPLUS® AAV6 packaging system leads to a 1.4-to-2.9-fold increase in VG vs competitors.

Enhanced infectivity when used with pPLUS® AAV-Helper

The use of pPLUS® AAV2 packaging system leads to a 1.8-to-5.7-fold increase in TU vs competitors.
The use of pPLUS® AAV6 packaging system leads to a 1.6-to-2.4-fold increase in TU vs competitors.

Readily available  

pPLUS® AAV-RC Range is available off-the-shelf for a fast and reliable supply in various pack sizes from 1 to 100mg 

Royaltyfree even for commercial use 

No royalties or licensing fees will be applied for the use of this product, whether it is used for research, clinical or commercial purpose. However, no right to amplify, replicate and/or duplicate the pPLUS® Plasmids will be conveyed to the end-users.  

Other sources to help you understand pPLUS® AAV-Helper better

Other Sources

Check our FAQs

These FAQs are organized by application to guide you to find the best answer possible.

Product Documents

You have access to all the documents related to the transfection reagent.

Polyplus Database

Search for publications in our Transfection Database with Polyplus transfection reagents

Lexicon

This lexicon will help you to understand the different terms related to Polyplus-transfection®.

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Resources

Articles

Optimizing Plasmid Ratios to Enhance rAAV Production

Webinars

Webinar replay: Next Generation of Genetic Engineered AAV Helper Plasmids

Visuals

Poster : Enhancing AAV productivity through Helper plasmid design and plasmid ratio optimization

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