pPLUS® AAV-Helper is a novel plasmid helper designed for AAV production. This plasmid has been optimized for triple transfection of HEK293 cells in s...
Who we are
Polyplus, part of Sartorius, is a leading upstream solutions provider for advanced biologic and cell and gene therapy production from research to commercial scale.
An innovator in nucleic acid delivery, the legacy portfolio features process-centric transfection reagents, kits, and support services for viral and non-viral delivery. Custom plasmid vector design and plasmid and protein manufacturing was integrated into the offer in 2022 to expand the products and services portfolio to help the industry optimize process economics while meeting strict scientific and regulatory standards.
Headquartered in Europe, the Polyplus team continues to grow globally with operations in the United States and Asia. Since July 2023, Polyplus is now part of Sartorius.
What we do
Did you know that we’ve made it possible for you to improve your lentiviral yields, while reducing the amount of DNA needed? FectoVIR®-LV is the brand new transfection reagent on the block ready to boost your productivity, reduce your cost and allow you to scale-up your process. The Cherry on top? we provide complementary DOE service to fast-track your optimization!
All Our Products and Services
Polyplus® free of charge viral vector DOE service is the combination of our expertise in the field of nucleic acid delivery and in DoE methodology.
Polyplus offers a comprehensive range of plasmid manufacturing services from DNA plasmid design to plasmid DNA manufacturing and analytical testing.
Obtain accurate and reliable full length plasmid sequencing with our Next Generation Sequencing service.
Polyplus provides an integrated service for design and production of tailor-made DNA plasmid through our unique and Innovative assembly technology.
FectoVIR®-LV transfection reagent designed to improve Lentiviral vector (LV) titers in HEK-293 suspension cell systems.
LipidBrick® IM21.7c is a novel cationic lipid dedicated to the formulation of LNPs for the development of mRNA-based vaccines and therapeutics.
in vivo-jetRNA®+ is a lipid-based transfection reagent composed of preformed liposomes specifically developed for in vivo mRNA delivery.
Available at research and GMP grade to intensify production of recombinant AAV rAAV viral vectors at any scale from benchtop to 2000L scale bioreactor...
in vivo-jetPEI® is a ready-to-use cationic polymer reagent recommended for in vivo transfection of DNA, siRNA, miRNA, shRNA and other oligonucleotide...
jetOPTIMUS® is an innovative cationic nanotechnology developed to improve DNA transfection efficiency in hard-to-transfect cells.
FectoCHO® expression system is optimized for culture and transient protein expression of all CHO cells.
PEIpro® is the leading PEI-based DNA transfection reagent that offers flexibility and scalability for viral vector manufacturing.
jetMESSENGER® is a designed for high mRNA transfection efficiency in primary cells, cancer cell lines, neurons, and stem cells.
High-throughput cDNA libraries screening is a valuable tool to study gene expression and regulation and protein interactions and functions.
FectoPRO is a transfection reagent specifically optimized for transient protein and antibody expression in CHO and HEK293 cells.
The delivery of protein and antibody using PULSin® represents a powerful approach for functional studies in live cells.
INTERFERin® provides very high silencing efficiency already at 1 nM siRNA and can be used in a wide variety of adherent and suspension cells....
jetPRIME® is a versatile DNA and siRNA transfection reagent that ensures high DNA transfection efficiency and excellent gene silencing.
Frequently Asked Questions
Here's the answer guide to all your questions.These FAQs are organized by application to guide you to find the best answer possible.
Search in the publication database with Polyplus transfection reagents or for transfection conditions
- Polyplus Launches Off-the-Shelf pPLUS® AAV-Helper Plasmid for enhanced AAV Production
- The Japanese Society for Gene and Cell Therapy
- Infographic : Polyplus solutions for viral vector production
- BioProcess International US East
- 7th edition, Cell and Gene Therapy World Asia
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Our Company Values
Growing profitably and acting responsibly towards all stakeholders
Driving change and progress internally and externally
Working in an energetic and rewarding environment
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Add value to Human life, where our mission is to develop cutting-edge delivery technologies to enable scientists to develop breakthrough nucleic acid-based therapies as treatment to improve Human health every step of the way from basic science to the clinic