in vivo-jetRNA®+ is a lipid-based transfection reagent composed of preformed liposomes specifically developed for in vivo mRNA delivery.

RNA/DNA Therapeutics
Gold standard for in vivo delivery of DNA, siRNA, shRNA and miRNA
Time-saving
Ready-to-use reagent that does not require formulation equipment
GMP grade availability
Manufactured according to both US and EU Guidelines
Successful
Excipient for in vivo delivery widely used from fundamental research to Human clinical trials
Renowned
Well-documented in vivo transfection technology with over 600 peer-reviewed publications
Type | Ready-to-use cationic polymer |
---|---|
Molecules delivered | DNA, siRNA, miRNA, shRNA, mRNA, saRNA or other oligonucleotides |
Biodistribution and Injection routes | Universal biodistribution: Any organ or tissue (depending on the injection route) |
Number of injections | 100 µl of in vivo-jetPEI® is sufficient to perform 15 to 25 intravenous injections in mice |
Storage | Store in vivo-jetPEI® at -20 ± 5°C. Do not freeze. |
Product documentation | Protocol |
Regulatory documentation | With GMP grade only: |
in vivo-jetPEI® is a ready-to-use cationic polymer reagent used for in vivo transfection of nucleic acids (DNA, siRNA, miRNA, shRNA and other oligonucleotides) in any animal model.
With more than 600 peer-reviewed publications, in vivo-jetPEI® is established in the field of in vivo delivery, whether for functional studies, oncology research as well as vaccination purposes. Additionally, in vivo-jetPEI® has the advantage of being available in 2 different quality grades (Research and GMP grades) to support our customers at each step of their development process.
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This lexicon will help you to understand the different terms related to Polyplus-transfection®.