Abstract

DNA transfection remains a limiting factor for many researchers working with primary cells and specific cell lines. Considering the limiting steps in these hard-to-transfect cell types and based on our knowledge and expertise in transfection, we have addressed this issue by developing a novel DNA transfection reagent, jetOPTIMUS®. This reagent improves DNA delivery and intracellular transport ending by higher gene expression in hard-to-transfect primary cells and cell lines. This reagent associates higher transfection efficiency and lower toxicity compared to the best commercially available competitors. DNA transfection reagent jetOPTIMUS® is easy to use and provides highly reproducible results.