Citation
- Authors: Wang L. et al.
- Year: 2019
- Journal: Nanoscale 11 22237-22242
- Applications: in vitro / Protein/Peptide/Antibody / PULSin
- Cell type: MGC-803
Description: Human gastric carcinoma
Known as: MGC803
Abstract
We developed a versatile and modular method for cytosolic protein delivery through metal ion-induced co-assembly of gold nanoclusters and proteins into supramolecular assemblies. The versatility and high efficiency of this strategy to assemble and deliver various proteins into living cells were demonstrated. Importantly, the activity of proteins was maintained during the delivery. This modular approach provides an exciting and promising new nano-platform for cytosolic protein delivery.