Citation

  • Authors: Beghini, Alessandro, Corlazzoli, Francesca, Del Giacco, Luca, Re, Matteo, Lazzaroni, Francesca, Brioschi, Matteo, Valentini, Giorgio, Ferrazzi, Fulvia, Ghilardi, Anna, Righi, Marco, Turrini, Mauro, Mignardi, Marco, Cesana, Clara, Bronte, Vincenzo, Nilsson, Mats, Morra, Enrica, Cairoli, Roberto. et al.
  • Year: 2012
  • Journal: Neoplasia 14 1236-IN45
  • Applications: in vitro / DNA / jetPEI
  • Cell type: HEK-293T
    Description: Human embryonic kidney Fibroblast
    Known as: HEK293T, 293T

Abstract

Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized by two molecularly distinct self-renewing leukemic stem cell (LSC) populations most closely related to normal progenitors and organized as a hierarchy. A requirement for WNT/