Citation
- Authors: Takeuchi, J. S., Perche, B., Migraine, J., Mercier-Delarue, S., Ponscarme, D., Simon, F., Clavel, F., Labrosse, B.
- Year: 2013
- Journal: Retrovirology
- Applications: in vitro / DNA / jetPEI
- Cell type: HEK-293T
Description: Human embryonic kidney Fibroblast
Known as: HEK293T, 293T
Abstract
BACKGROUND:
HIV-2, which was transmitted to humans from a distant primate species (sooty mangabey), differs remarkably from HIV-1 in its infectivity, transmissibility and pathogenicity. We have tested the possibility that a greater susceptibility of HIV-2 capsid (CA) to the human restriction factor TRIM5