pPLUS® AAV-RC range is a set of ready-to-use RepCap plasmids for AAV production of various serotypes through triple transfection. Optimized for use w...

Cell and Gene Therapy
Transfection reagent for large scale rAAV manufacturing
Process economics
High AAV productivity expands the number of doses per batch to reduce manufacturing cost
Industrial scalability
Designed for large scale with low complexation volume, long complex stability and high reproducibility
GMP grade availability
Validated Manufacturing process following ICH Q7 guidelines, provided with full regulatory documentation
Risk Mitigation
Both residual test and toxicity statement enable to mitigate risks and ensure patient safety
Product information | Ready to use, synthetic and free of any animal-origin component |
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Applications | rAAV (Adeno-Associated Virus) manufacturing using HEK-293 derivative cells |
Number of transfections | 1 L of FectoVIR®-AAV transfection reagent is sufficient to transfect on average 500 L of cell culture (using standard conditions) |
Storage condition | Store FectoVIR®-AAV at 5 °C ± 3°C. |
Product documentation | Protocol |
Regulatory documentation (FectoVIR®-AAV GMP only) | Certificate of compliance |
FectoVIR®-AAV is a novel generation of synthetic transfection reagent specifically developed for industrial scale production of recombinant AAV (rAAV) in both suspension and adherent HEK-293 derivative cell systems. FectoVIR®-AAV transfection reagent guarantees higher rAAV titers, improves scalability for large scale production and de-risks manufacturing process with it’s availability at pharma GMP grade. FectoVIR®-AAV-GMP is manufactured under a validated and aseptic process in compliance with ICH Q7, GMP part II guidelines, the quality grade of reference for active pharmaceutical ingredients (API).
Reference Number | Product | Amount of reagent | |
---|---|---|---|
101000044 | FectoVIR®-AAV | FectoVIR®-AAV 1 mL | |
101000022 | FectoVIR®-AAV | FectoVIR®-AAV 10 mL | |
101000004 | FectoVIR®-AAV | FectoVIR®-AAV 100 mL | |
101000054 | FectoVIR®-AAV | FectoVIR®-AAV 1 L | |
102000006 | FectoVIR®-AAV GMP | FectoVIR®-AAV GMP 100 mL Bottle | |
102000009 | FectoVIR®-AAV GMP | FectoVIR®-AAV GMP 1 L Bag | |
101000137 | ***NODISPLAY*** | ***NODISPLAY*** | ***NODISPLAY*** |
120-001 | ***NODISPLAY*** | ***NO DISPLAY*** 1 ml | ***NODISPLAY*** |
120-01L | ***NODISPLAY*** | ***NO DISPLAY*** 1L | ***NODISPLAY*** |
120-010 | ***NODISPLAY*** | ***NO DISPLAY*** 10 ml | ***NODISPLAY*** |
120-100 | ***NODISPLAY*** | ***NO DISPLAY*** 100 ml | ***NODISPLAY*** |
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Search for publications in our Transfection Database with Polyplus transfection reagents
This lexicon will help you to understand the different terms related to Polyplus-transfection®.